Thermo Fisher Scientific SULT2B1 Monoclonal Antibody (2142CT1553.26.63)

Applications

• Western Blot (WB): Tested dilution 1:8,000

Product Specifications

Target Information

Cytosolic sulfotransferases (STs or SULTs) catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters.
Her et al. (1998) identified an EST with homology to ST enzymes. By PCR with human placental and prostate cDNA as template, they isolated two alternatively spliced cDNAs, identical throughout most of their sequences but having different 5-prime ends.
The shorter cDNA, SULT2B1a, encodes a protein of 350 amino acids; the longer cDNA, SULT2B1b, encodes a 365-amino acid protein.
Genomic PCR analysis revealed that the gene encoding both cDNAs, SULT2B1, contains seven exons, with two alternative first exons being used to generate SULT2B1a and SULT2B1b.
Northern blot analysis revealed that the SULT2B1 gene is expressed as a 1.4-kb transcript predominantly in prostate, placenta, and trachea.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.