Thermo Fisher Scientific FGF23 Polyclonal Antibody

Thermo Fisher Scientific FGF23 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:2,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human FGF23.

Target Information

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family, which possesses broad mitogenic and cell survival activities. FGF family members are involved in various biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
FGF23 inhibits renal tubular phosphate transport. Mutations in this gene are associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate wasting disorder. Elevated expression levels are found in oncogenic hypophosphatemic osteomalacia, a disease caused by abnormal phosphate metabolism. Mutations also cause familial tumoral calcinosis with hyperphosphatemia.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.