Thermo Fisher Scientific ASCC1 Monoclonal Antibody (OTI6G5), TrueMAB
ASCC1 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC, Flow 등 다양한 응용에 적합. 인간 유래 단백질로부터 제작되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G5 |
| Immunogen | Full length human recombinant protein of human ASCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.41 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex acts as a transcriptional coactivator, playing an important role in gene transactivation by multiple transcription factors including AP-1, NF-kB, and SRF. The encoded protein contains an N-terminal KH-type RNA-binding motif required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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