Thermo Fisher Scientific RAB11FIP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 330-540 of human RAB11FIP1 (NP_079427.4). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAB11FIP1,uniProtId:Q6WKZ4-4,ncbiNodeId:9606,antigenRange:330-540,antigenLength:1283,antigenImageFileName:PA5-121227_RAB11FIP1_Q6WKZ4-4_Rabbit.svg,antigenImageFileNamePDP:PA5-121227_RAB11FIP1_Q6WKZ4-4_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.72 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914799

Product Specific Information

Positive test controls include: HeLa, HepG2, COS-7. The target is usually found in the following locations: Cytoplasmic vesicle, Recycling endosome, phagosome membrane.

Immunogen sequence: EAKGEIKDSS PSSSPSPKGF RKKHLFSSTE NLAAGSWKEP AEGGGLSSDR QLSESSTKDS LKSMTLPSYR PAPLVSGDLR ENMAPANSEA TKEAKESKKP ESRRSSLLSL MTGKKDVAKG SEGENPLTVP GREKEGMLMG VKPGEDASGP AEDLVRRSEK DTAAVVSRQG SSLNLFEDVQ ITEPEAEPES KSEPRPPISS PRAPQTRAVK P

Target Information

Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein. Rab11-FIP1, by interacting with Rab GTPases, is involved in the endosomal recycling process and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis. Localized to the recycling endosome, the cytoplasmic membrane and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing. As the most highly expressed isoform, isoform two of Rab11-FIP1 is expressed in brain, lung, testis, small intestine, spleen and heart. Isoform two of Rab11-FIP1 also has been found to form a homooligomer and is believed to interact with many Rab GTPases, including Rab 4A, Rab 11A, Rab 11B and Rab 25.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.