Thermo Fisher Scientific SPINK7 Polyclonal Antibody
SPINK7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 IHC(P) 분석에 적합. Human 및 Mouse 시료 반응성. Affinity chromatography로 정제된 액상 항체로, -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SPINK7 (Accession P58062), corresponding to amino acid residues T48–C85 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850257 |
Product Specific Information
Antibody detects endogenous levels of total ISK7.
Target Information
SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein containing one Kazal-like domain. SPINK7 is thought to be a serine protease inhibitor.
The SPINK7 gene maps to human chromosome 5, which contains approximately 181 million base pairs and around 1,000 genes. Chromosome 5 is associated with several genetic disorders, including Cockayne syndrome (ERCC8 gene), familial adenomatous polyposis (APC gene), and Treacher Collins syndrome (TCOF1 gene). Deletions in chromosome 5 can lead to Cri du chat syndrome and are common in therapy-related acute myelogenous leukemias and myelodysplastic syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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