Thermo Fisher Scientific Bcl-6 (Follicular Lymphoma Marker) Monoclonal Antibody (SPM602)
Bcl-6 단클론 항체(SPM602)는 인간 및 마우스 반응성을 가지며, IHC, ICC, Flow Cytometry 등에 사용 가능. Recombinant human Bcl-6 단백질을 면역원으로 제작. Protein A/G 정제, 1 mg/mL 농도, PBS(pH 7.4)에 보존. 연구용으로만 사용 가능.
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- 604-MSM1X-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.125–0.25 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM602 |
| Immunogen | Recombinant human Bcl-6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and Bcl-6 rearrangements have been detected in 33–45% of diffuse large B cell lymphomas.
Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and in nodular, lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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