Thermo Fisher Scientific HAND2 Polyclonal Antibody
HAND2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 최적화됨. 인간 반응성, 토끼 IgG 호스트. 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 심장 발생 및 발달 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 81–110 amino acids from the central region of human HAND2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552496 |
Product Specific Information
This antibody is predicted to react with chicken, mouse, rat, and Xenopus based on sequence homology.
Target Information
The HAND2 protein belongs to the basic helix-loop-helix family of transcription factors. It is one of two closely related HAND proteins, asymmetrically expressed in developing ventricular chambers and essential for cardiac morphogenesis. HAND2 functions in the formation of the right ventricle and aortic arch arteries, and plays a key role in limb and branchial arch development. These properties implicate it as a mediator of congenital heart disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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