Thermo Fisher Scientific SPNS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N terminal region of human SPNS1 (aa 2-51). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPNS1,uniProtId:Q9H2V7-1,ncbiNodeId:9606,antigenRange:2-51,antigenLength:528,antigenImageFileName:PA5-113920_SPNS1_Q9H2V7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-113920_SPNS1_Q9H2V7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2884435

Product Specific Information

Immunogen sequence: AGSDTAPFLS QADDPDDGPV PGTPGLPGST GNPKSEEPEV PDQEGLQRIT

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Predicted homology: Cow: 92%; Dog: 91%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Target Information

SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.