Thermo Fisher Scientific MEKK6 Polyclonal Antibody
Human MEKK6 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제됨. PBS, 40% glycerol 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Concentration: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MEKK6. Recombinant protein control fragment (Product # RP-101334) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643869 |
Product Specific Information
Immunogen sequence:
EEPASPEESS GLSLLHQESK RRAMLAAVLE QELPALAENL HQEQKQEQGA RLGRNHVEEL LRCLGAHIHT PNRR
Highest antigen sequence identity:
- Mouse: 81%
- Rat: 84%
Target Information
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK).
MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK.
The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells.
MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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