Thermo Fisher Scientific ABCB7 Polyclonal Antibody
ABCB7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, C-말단 합성 펩타이드로 면역화되었습니다. 0.5 mg/mL 농도의 액상 형태로, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human ABCB7 (aa 633–682) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610110 |
Product Specific Information
Peptide sequence:
DEATSSLDSI TEETILGAMK DVVKHRTSIF IAHRLSTVVD ADEIIVLDQG
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 92%
Target Information
The membrane-associated protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein belongs to the MDR/TAP subfamily, involved in multidrug resistance and antigen presentation. The gene encodes a half-transporter responsible for heme transport from mitochondria to cytosol and may play a role in metal homeostasis.
Mutations in this gene are associated with X-linked sideroblastic anemia with ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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