Thermo Fisher Scientific GCK Recombinant Rabbit Monoclonal Antibody (23GB5845)
Thermo Fisher Scientific의 GCK Recombinant Rabbit Monoclonal Antibody (23GB5845)은 인간 Glucokinase를 표적으로 하는 고특이성 항체입니다. Western blot 및 유세포분석(Flow Cytometry)에 적합하며, HEK293F 시스템에서 발현된 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA55292x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GCK Recombinant Rabbit Monoclonal Antibody (23GB5845)
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5845 |
| Immunogen | A synthesized peptide derived from human Glucokinase (250–465AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.
Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver.
The protein localizes to the outer membrane of mitochondria.
In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant.
Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2), and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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