Thermo Fisher Scientific CD8 beta Polyclonal Antibody
Human CD8B 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. PBS/glycerol buffer에 보존되며 연구용으로만 사용 가능.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CD8B. Recombinant protein control fragment (Product #RP-105806) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790222 |
Product Specific Information
Immunogen sequence:
EGISGTFVPQ CLHGYYSNTT TSQKLLNPWI LK
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system.
The CD8 antigen acts as a coreceptor with the T-cell receptor to recognize antigens presented by an antigen-presenting cell (APC) in the context of class I MHC molecules.
The functional coreceptor may be a homodimer (two alpha chains) or a heterodimer (one alpha and one beta chain). Both chains share significant homology to immunoglobulin variable light chains.
This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane-associated or secreted isoforms have been described. A pseudogene located on chromosome 2 has also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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