Thermo Fisher Scientific C20orf20 Polyclonal Antibody
C20orf20 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성 보유. Protein A로 정제된 고순도 항체로 핵 내 NuA4 HAT 복합체 연구에 적합.
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Thermo Fisher Scientific C20orf20 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human C20orf20 (amino acids 121–204) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4) with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
C20orf20, also known as MRG/MORF4L-binding protein or Up-regulated in colon cancer 4 (Urcc4), is a 204-amino acid protein belonging to the EAF7 family.
It localizes in the nucleus and is a component of the NuA4 histone acetyltransferase (HAT) complex, which is involved in transcriptional activation by acetylation of nucleosomal histones H4 and H2A.
This modification can alter nucleosome-DNA interactions and promote binding of modified histones to proteins that positively regulate transcription.
The NuA4 complex may be required for activation of transcriptional programs related to oncogene-mediated growth induction, tumor suppressor-mediated growth arrest, replicative senescence, apoptosis, and DNA repair.
C20orf20 undergoes phosphorylation and acetylation, with a molecular weight of approximately 25–30 kDa.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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