Thermo Fisher Scientific Human CXXC5 Synthetic Peptide
인간 CXXC5 단백질의 N-말단 부위 15개 아미노산 서열로 구성된 합성 펩타이드. PA5-21080 항체의 블로킹 펩타이드로 사용 가능. Wnt 신호전달 조절 연구에 활용. 액상 형태, 200 µg/mL 농도, PBS 버퍼에 0.1% BSA 포함.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to a 15 amino acid sequence near the amino terminus of human CXXC5.
PEP-1194 can be used as a blocking peptide with polyclonal antibody PA5-21080.
Target Information
CXXC5 is a zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development.
CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitating the response of the stem cells to Wnt3a.
Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together they are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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