Thermo Fisher Scientific EPB41L4B Polyclonal Antibody
인간 EPB41L4B 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품. PBS/glycerol buffer에 보관하며, 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EPB41L4B. Recombinant protein control fragment (Product #RP-92888). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641061 |
Product Specific Information
Immunogen sequence:
PLHININKAE EKKVSEKTLQ TPLLPSPVAD HVKCNILKAQ LENASRVNIQ GGKEESPFVN INKKSSLQDA SVRSPIPIRV ETAQPAVEKP EIKPPRVRKL TRQYSFDEDD LPP
Highest antigen sequence identity to orthologs:
- Mouse: 91%
- Rat: 92%
Target Information
Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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