Thermo Fisher Scientific ARIH1 Polyclonal Antibody
인간 ARIH1 단백질을 인식하는 염소 폴리클로날 항체. Western blot 및 IHC(P) 검증 완료. 합성 펩타이드(aa 544-557)를 면역원으로 사용. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HEGYEKDLWEYIED) corresponding to the C-terminus amino acids of ARIH1 (aa 544–557) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984570 |
Product Specific Information
- Predicted to react with bovine and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
E3 ubiquitin-protein ligase involved in ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3. Functions as an atypical E3 ubiquitin-protein ligase by associating with cullin-RING ubiquitin ligase (CRL) complexes and mediating the initial ubiquitin addition to CRL substrates. Activated upon binding to neddylated CRL complexes. Plays roles in protein translation in response to DNA damage by mediating ubiquitination of EIF4E2, and may regulate degradation of the LINC complex member SUN2, influencing nuclear morphology. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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