Thermo Fisher Scientific PGRP-1b Polyclonal Antibody
PGRP-1b 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 최적화되어 있습니다. 인간 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 면역 인식 관련 연구에 적합합니다.
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 242–268 amino acids from the central region of human PGLYRP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900924 |
Target Information
The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever.
Recently, a family of proteins called peptidoglycan recognition proteins (PGRPs) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria.
Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and is an excellent target for recognition by the eukaryotic innate immune system.
The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-Iβ) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver, which participates in host defenses by producing acute phase proteins and clearing microorganisms from blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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