Thermo Fisher Scientific ArfGAP3 Polyclonal Antibody
ArfGAP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 단백질에 반응하며 액상 형태로 제공, 4°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 466 and 516 of human ADP-ribosylation factor GTPase activating protein 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Orangutan based on 100% sequence identity
Target Information
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins.
It promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for dissociation of coat proteins from Golgi-derived membranes and vesicles.
Dissociation of coat proteins is necessary for vesicle fusion with target compartments.
The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been identified.
This gene was originally known as ARFGAP1, now referring to a related but distinct gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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