Thermo Fisher Scientific Tensin 3 Polyclonal Antibody
Human Tensin 3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공. 세포 구조 및 신호전달 연구용에 이상적.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | View publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | View publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Tensin 3. Recombinant protein control fragment (Product #RP-103213) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.30 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648381 |
Product Specific Information
Immunogen sequence:
HLGPFTCHKS SQNSLLSDGF GSNVGEDPQG TLVPDLGLGM DGPYERERTF GSREPKQPQP LLRKPSVSAQ MQAYGQSSYS TQTWVRQQQM VVAHQYSFAP DGEAR
Highest antigen sequence identity to orthologs:
- Mouse: 75%
- Rat: 75%
Target Information
The Tensin (Tns) family of proteins is involved in maintaining cellular structure by anchoring actin filaments at focal adhesions through F-actin binding and capping activities. Tns proteins contain an SH2 domain and can be phosphorylated, indicating a role in signal transduction. These characteristics suggest that Tns proteins link the cytoskeleton and signal transduction pathways.
Tns3 (also known as TEM6 or TENS1) localizes to focal adhesions of the plasma membrane. It is predominantly expressed in thyroid and placenta but also found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle, and white blood cells. Tns3 is essential for proper growth and development, as indicated by growth retardation and death in Tns3 knockout mice.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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