Thermo Fisher Scientific MAP2K4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MAP2K4 (MKK4/MEK4). IHC(P) 및 ICC/IF에 사용 가능하며, 무보존제 액상 형태로 제공됩니다. Protein A 및 항원 친화 정제, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human MKK4/MEK4/MAP2K4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788066 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human MKK4/MEK4/MAP2K4.
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase (mitogen-activated protein kinase 4) belonging to the STE7 family. It phosphorylates and activates JNK1/2 and p38, preferentially targeting the tyrosine residue of JNKs.
MAP2K4 mediates various physiological and pathophysiological processes, including cellular stress and inflammatory cytokine responses. It plays a role in carcinogenesis; loss-of-function mutations have been observed in lung and pancreatic tumors, while pro-oncogenic roles have also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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