Thermo Fisher Scientific GPNMB Polyclonal Antibody
GPNMB 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF에 사용 가능. 인간 시료에서 검증되었으며 1 mg/mL 농도의 액상 형태. SKBR3 세포에서 양성 대조로 추천되며 연구용으로 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 181–407 of Human GPNMB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2545350 |
Product Specific Information
- Recommended positive controls: SKBR3
- Predicted reactivity: Rhesus Monkey (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a type I transmembrane glycoprotein homologous to the pMEL17 precursor, a melanocyte-specific protein.
GPNMB shows expression in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic cell lines.
It may be involved in growth delay and reduction of metastatic potential.
Two transcript variants encoding different isoforms have been identified for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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