Thermo Fisher Scientific Cyclin C Polyclonal Antibody
Cyclin C 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 다양한 종에서 예측 반응성을 가집니다. 고순도 정제 및 안정적 저장 조건으로 연구용에 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 221–249 amino acids from the C-terminal region of human Cyclin C (CCNC) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2072404 |
Product Specific Information
This antibody is predicted to react with bovine, chicken, mouse, rat, and Xenopus based on sequence homology.
Target Information
Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock-out of the CLN genes in Saccharomyces cerevisiae.
Cyclin C is a nuclear protein present in a multiprotein complex and interacts with cdk8, a novel protein kinase of the cdk family.
It is suggested that Cyclin C and cdk8 control RNA polymerase II function. Human cdk8–Cyclin C may be functionally associated with the mammalian transcription apparatus, possibly relaying growth regulatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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