Thermo Fisher Scientific A2M Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Chicken 유래 Polyclonal A2M 항체로 Western blot 및 ELISA에 사용 가능. 1 mg/mL 농도의 액상 형태로 제공되며 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length protein (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2288844 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Alpha 2-Macroglobulin (A2M) is an approximately 720-kDa homotetrameric glycoprotein composed of four identical ~180 kDa subunits.
A2M shares with other alpha-macroglobulins, such as complement components C3, C4, and pregnancy zone protein (PZP), an extraordinary binding capacity for a variety of ligands.
This enables alpha-macroglobulins to act as humoral defense barriers against foreign peptides in plasma.
A2M captures virtually any proteinase, functioning as a panprotease inhibitor.
In Alzheimer’s disease patients, A2M has been localized to diffuse amyloid plaques, suggesting an important role in AD etiopathology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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