Thermo Fisher Scientific NAT1 Polyclonal Antibody
Thermo Fisher Scientific의 NAT1 Polyclonal Antibody는 인간 NAT1 단백질을 인식하는 토끼 유래 다클론 항체로, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–290 of human NAT1 (NP_001153646.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.22 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855424 |
Product Specific Information
Immunogen sequence:
MDIEAYLERI GYKKSRNKLD LETLTDILQH QIRAVPFENL NIHCGDAMDL GLEAIFDQVV RRNRGGWCLQ VNHLLYWALT TIGFETTMLG GYVYSTPAKK YSTGMIHLLL QVTIDGRNYI VDAGFGRSYQ MWQPLELISG KDQPQVPCVF RLTEENGFWY LDQIRREQYI PNEEFLHSDL LEDSKYRKIY SFTLKPRTIE DFESMNTYLQ TSPSSVFTSK SFCSLQTPDG VHCLVGFTLT HRRFNYKDNT DLIEFKTLSE EEIEKVLKNI FNISLQRKLV PKHGDRFFTI
Target Information
Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates involved in detoxification of various drugs. Certain alleles with high N-acetyltransferase activity are associated with colon and urinary bladder cancers, as NATs also bioactivate carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins that play active roles in detoxification of arylamine and hydrazine drugs. N-acetylation polymorphism is determined by NAT activity levels in liver tissues and is linked to drug action and toxicity. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 corresponds to rodent NAT-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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