Thermo Fisher Scientific eIF3H/EIF3S3 Polyclonal Antibody
Rabbit polyclonal antibody against human eIF3H, validated for Western blot and immunoprecipitation. Targets region 302–352 of eIF3H involved in translation initiation. Supplied as unconjugated liquid at 1 mg/mL, stored at 4°C. For research use only.
- 카탈로그번호
- A301754Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific eIF3H/EIF3S3 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 302 and 352 of human eukaryotic translation initiation factor 3 subunit H (EIF3H) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
eIF3H is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, required for several steps in the initiation of protein synthesis.
The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5 to form the 43S pre-initiation complex (43S PIC).
It stimulates mRNA recruitment and scanning for AUG recognition, assists in disassembly and recycling of post-termination ribosomal complexes, and prevents premature joining of the 40S and 60S subunits.
eIF3H selectively initiates translation of mRNAs involved in cell proliferation, differentiation, and apoptosis, utilizing different RNA stem-loop binding modes for activation or repression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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