Thermo Fisher Scientific SLC6A11 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the C-terminal of human SLC6A11 (aa 577-626). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC6A11,uniProtId:P48066-1,ncbiNodeId:9606,antigenRange:577-626,antigenLength:632,antigenImageFileName:PA5-45004_SLC6A11_P48066-1_Rabbit.svg,antigenImageFileNamePDP:PA5-45004_SLC6A11_P48066-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2608709

Product Specific Information

Peptide sequence: EGTLPEKLQK LTTPSTDLKM RGKLGVSPRM VTVNDCDAKL KSDGTIAAIT

Sequence homology: Cow: 85%; Dog: 92%; Guinea Pig: 92%; Horse: 85%; Human: 100%; Mouse: 77%; Rabbit: 93%; Rat: 92%

Target Information

Slc6a11 encode GABA transporters that are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) and mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters have been identified and localized to neurons and glia. The protein encoded by the Slc6a11 gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in the Slc6a11 gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for the Slc6a11 gene. Diseases associated with SLC6A11 include Tricuspid Valve Stenosis and Pulmonary Valve Insufficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.