
Thermo Fisher Scientific RNF139 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
1:100-1:500
Immunohistochemistry (Frozen) (IHC (F))
1:100-1:500
Immunocytochemistry (ICC/IF)
1:50-1:200
ELISA (ELISA)
1:500-1:1,000
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human RNF139, amino acids 501-600. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
RNF139,
uniProtId:
Q8WU17-1,
ncbiNodeId:
9606,
antigenRange:
501-600,
antigenLength:
664,
antigenImageFileName:
BS-6096R_RNF139_Q8WU17-1_Rabbit.svg,
antigenImageFileNamePDP:
BS-6096R_RNF139_Q8WU17-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a ttranslocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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