Thermo Fisher Scientific YAP1 Polyclonal Antibody
YAP1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot과 Immunoprecipitation에 적합. Human YAP1의 250–300 아미노산 영역을 면역원으로 제작. Hippo 신호전달 연구 및 암 관련 단백질 발현 분석에 활용 가능. 4°C 보관, 액상 형태.
- 카탈로그번호
- A302308Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific YAP1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 250 and 300 of Human Yes-associated protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with X. laevis, X. tropicalis, and Dog
Target Information
YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, acting as a transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP functions as both coactivator and corepressor and is a critical downstream regulatory target in the Hippo signaling pathway, which controls organ size and tumor suppression by restricting proliferation and promoting apoptosis. It also plays essential roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene result in coloboma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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