Thermo Fisher Scientific F131C Polyclonal Antibody
Human F131C 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol, 0.02% sodium azide) 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human F131C. Recombinant protein control fragment (Product # RP-94504) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641185 |
Product Specific Information
Immunogen sequence:
AEDEHYCCLP DELREARFAA GVAEQFAITE ATLSAWSSLD EEELHPENSP QGIVQLQDLE SIYLQDSLPS G
Highest antigen sequence identity to orthologs:
- Mouse: 90%
- Rat: 89%
Target Information
The F131C gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, protecting tissues such as brain and lungs from oxidative stress.
Proteolytic processing of the encoded protein forms two distinct homotetramers:
- Type C subunit: Intact protein, high affinity for heparin, anchored to the extracellular matrix (ECM)
- Type A subunit: Cleaved form, low affinity for heparin, does not interact with ECM
A mutation in this gene may be associated with increased heart disease risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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