Thermo Fisher Scientific Fra1 Polyclonal Antibody
Fra1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, Human 시료에 반응. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Fra1 (amino acids 37–103, UniProt ID: P15407-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662584 |
Product Specific Information
Immunogen sequence:
LVPSINTMSGS QELQWMVQPH FLGPSSYPRP LTYPQYSPPQ PRPGVIRALG PPPGVRRRPC EQISPE
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 96%
Target Information
The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1, and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by various agents and function as transcriptional regulators for several genes. Unlike c-Jun proteins, which form homo- and heterodimers that bind specific DNA response elements, c-Fos proteins are active only as heterodimers with members of the Jun gene family. Selected ATF/CREB family members can also form leucine zipper dimers with Fos and Jun, resulting in dimers with differential specificity and affinity for AP-1 and CRE sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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