Thermo Fisher Scientific NES Monoclonal Antibody (UMAB267), UltraMAB
인간 Nestin 단백질을 인식하는 UMAB267 단클론 항체로, IHC(P)에서 1:200 희석 비율로 사용됩니다. 줄기세포 및 신경세포 표지 연구에 적합하며, 액상 형태로 -20°C 보관이 필요합니다. 연구용으로만 사용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB267 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 99–349 of human NES produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells.
It is widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells.
Nestin is also a superior angiogenic marker for evaluating neovascularity of endothelial cells in tumors.
Highly specific antibodies to human Nestin can help characterize progenitor cells differentiating into distinct lineages, enhance the therapeutic potential of human neural stem/progenitor cells, and identify neuroepithelial tumor cells.
Nestin expression has also been observed in pancreatic hematopoietic stem cell populations and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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