Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI1A6), TrueMAB
TGIF1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot과 IHC(Paraffin)에 적합. Human TGIF1 전체 길이 단백질로부터 제작. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A6 |
| Immunogen | Full length human recombinant protein of human TGIF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter.
The protein acts as a transcriptional co-repressor of SMAD2 and may participate in nuclear signal transmission during development and in adulthood.
Mutations in this gene are associated with holoprosencephaly type 4, a structural anomaly of the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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