Thermo Fisher Scientific CD264 (TRAIL-R4) Recombinant Rabbit Monoclonal Antibody (10Y1N4)
TRAIL-R4 (CD264)을 인식하는 재조합 토끼 단클론 항체. Western blot, IHC(P), ELISA에 적합. 인간, 마우스, 랫트 반응성. HEK293 발현 시스템 사용, 액상 형태로 제공. -20°C 보관, 동결/해동 반복 피할 것.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10Y1N4 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 287–386 of human DCR2 (Q9UBN6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911967 |
Product Specific Information
- Positive test controls include: Mouse liver, Mouse kidney, Rat liver, Rat kidney.
- Immunogen sequence:
PTQVSEQEIQ GQELAELTGV TVELPEEPQR LLEQAEAEGC QRRRLLVPVN DADSADISTL LDASATLEEG HAKETIQDQL VGSEKLFYEE DEAGSATSCL
Target Information
TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines.
A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation but differs in its inability to induce apoptosis.
Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression.
The human TRAIL-R4 gene has been mapped to chromosome 8p22–21, clustered with three other TRAIL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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