Thermo Fisher Scientific GPX6 Polyclonal Antibody
Thermo Fisher Scientific의 GPX6 폴리클로날 항체로, Rat 시료에서 Western blot 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제된 Rabbit IgG 항체이며, -20°C에서 보관. 산화적 손상 방어 관련 GPX6 단백질 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:50–1:400 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Glutathione Peroxidase 6 (Olfactory). Antigen corresponds to amino acid range 20–221 of the target protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903643 |
Target Information
The protein encoded by this gene belongs to the glutathione peroxidase family, which catalyzes the reduction of hydrogen peroxide, organic hydroperoxides, and lipid hydroperoxides, protecting cells from oxidative damage. Several isozymes exist in vertebrates with varying cellular locations and substrate specificities. Expression has been observed in embryos and olfactory epithelium, although the precise function is not fully known. In humans, this isozyme is a selenoprotein containing selenocysteine (Sec) at its active site, encoded by the UGA codon. The 3′ UTRs of selenoprotein mRNAs contain a conserved SECIS element that allows UGA to be recognized as a Sec codon rather than a stop signal. In mouse and rat orthologs, this residue is replaced by cysteine (Cys), and their mRNAs lack the SECIS element.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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