Thermo Fisher Scientific PIG3 Polyclonal Antibody
PIG3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%)이며, PBS/glycerol buffer에 보존됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 230–286 of Human PIG3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803187 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation.
This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death.
It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence.
p53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence.
The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53.
It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.
At least two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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