Thermo Fisher Scientific NPAS2 Polyclonal Antibody
Human NPAS2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 항원을 사용하여 제작되었으며, 액상 형태로 제공됩니다. PBS/glycerol buffer에 보관하며 -20°C에서 안정적입니다.
- 카탈로그번호
- PA5103973
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NPAS2 (Accession Q99743), corresponding to amino acid residues P179–T229 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853305 |
Product Specific Information
Antibody detects endogenous levels of total NPAS2.
Target Information
Members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family are transcription factors containing a bHLH DNA-binding domain located amino-terminal to a PAS domain.
Neuronal PAS domain protein 2 (NPAS2, also designated PAS4/MOP4) is a member of the bHLH-PAS family and the PAS superfamily.
NPAS2, mapped to chromosome 2p11.2–2q13, is primarily expressed in neurons during the first week of postnatal development.
Its expression pattern matches the development of learning and memory, particularly in the frontal association and limbic forebrain pathways.
NPAS2 may play a regulatory role in long-term memory development and complex sensory information processing.
NPAS2 and MOP3 form a transcriptionally active heterodimer that binds to a CACGTGA-containing DNA element, driving transcription from a linked luciferase reporter gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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