Thermo Fisher Scientific WHSC2 Polyclonal Antibody
WHSC2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Thermo Fisher Scientific WHSC2 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human WHSC2. Recombinant protein control fragment (Product #RP-104783) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664742 |
Product Specific Information
Immunogen sequence:
DTGSLNLELEE QNPNVQDILG ELREKVGECE ASAMLPLECQ YLNKNALTTL AGPLTPPVKH FQLKRKPKSA TLRAELLQKS TET
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
The WHSC2 gene is expressed ubiquitously, with higher levels in fetal tissues than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. The gene is mapped to the 165 kb WHS critical region and may play a role in WHS or Pitt-Rogers-Danks syndrome phenotypes.
The encoded protein can react with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting potential use in specific cancer immunotherapy. It is also part of the NELF (negative elongation factor) complex involved in RNA polymerase II transcription elongation regulation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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