Thermo Fisher Scientific WWOX Polyclonal Antibody
WWOX 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot, ICC/IF, IP에 사용 가능하며, 비결합(unconjugated) 형태로 제공. 세포 기능 및 종양 억제 관련 연구에 적합.
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Thermo Fisher Scientific WWOX Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Immunoprecipitation (IP) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | RLAFTVDDNPTKPTTRQRY (a.a. 89–107) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
WW domain-containing proteins are found in all eukaryotes and play an important role in regulating various cellular functions such as protein degradation, transcription, and RNA splicing.
This gene encodes a protein containing 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD).
Highest normal expression is detected in hormonally regulated tissues including testis, ovary, and prostate.
This pattern and the SRD domain suggest a role in steroid metabolism.
The encoded protein shares over 90% identity with the mouse protein, an essential mediator of TNF-alpha-induced apoptosis, implying a similar role in human apoptosis and tumor suppression.
Alternative splicing generates transcript variants encoding distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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