Thermo Fisher Scientific MRGD Polyclonal Antibody
MRGD 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 검증됨. 베타-알라닌 관련 신호전달 연구에 활용 가능. 동결건조 형태로 제공되며, 재구성 후 -20°C에 보관. 연구용 시약으로만 사용.
- 카탈로그번호
- PA577493
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)KSHRLQESLGAVLGR, corresponding to amino acid residues 285–299 of rat MRGPRD |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736163 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
May regulate nociceptor function and/or development, including the sensation or modulation of pain.
Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evokes Ca(2+) influx in cells expressing the receptor.
Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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