Thermo Fisher Scientific SPARC/Osteonectin Monoclonal Antibody (OSTN/3759)
인간 SPARC 단백질을 인식하는 단클론 항체로, Western blot 및 면역조직화학에 적합. 고순도 Protein A/G 정제, 1 mg/mL 농도. 연구용으로만 사용 가능하며, 종양 억제 및 세포 형태 변화 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OSTN/3759 |
| Immunogen | Recombinant fragment (around aa1–200) of human SPARC protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPARC gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified and is involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but also correlated with metastasis due to cell shape changes that promote tumor cell invasion. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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