Thermo Fisher Scientific Varp Polyclonal Antibody
Western blot 및 Immunoprecipitation에 적합한 Rabbit Polyclonal Antibody. Human Varp 단백질(ANKRD27)에 특이적으로 반응하며, 액상 형태로 제공. 항원 친화 크로마토그래피로 정제되었으며, 4°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1000 and 1050 of Human Vps9 Domain and Ankyrin-Repeat-Containing Protein (ANKRD27, UniProt ID: Q96NW4-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
May be a guanine exchange factor (GEF) for Rab21, Rab32, and Rab38, regulating endosome dynamics.
May regulate VAMP7 participation in membrane fusion events by inhibiting SNARE complex formation.
Involved in peripheral melanosomal distribution of TYRP1 in melanocytes through vesicle trafficking with Rab32, Rab38, and VAMP7.
Regulates neurite growth and Golgi sorting of VAMP7, involving kinesin heavy chain isoform 5 proteins, GOLGA4, RAB21, and MACF1.
Required for colocalization of VAMP7 and Rab21 on TGN sites and involved in GLUT1 endosome-to-plasma membrane trafficking.
Regulates proper trafficking of melanogenic enzymes TYR, TYRP1, and DCT/TYRP2 to melanosomes in melanocytes.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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