Thermo Fisher Scientific ZMIZ2 Polyclonal Antibody
Human ZMIZ2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 0.93 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 569–818 of Human ZMIZ2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.93 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548745 |
Product Specific Information
- Recommended positive control: IMR32
- Predicted reactivity: Mouse (92%), Rat (93%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated STAT)-like protein and a transcriptional coactivator. ZIMP7 is most abundantly expressed in testis. Its C-terminal proline-rich domain exhibits intrinsic transcriptional activity, which is inhibited by the N-terminus in the full-length form. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhance Androgen Receptor (AR)-mediated transcription. The interaction between ZIMP7 and the SWI/SNF complex suggests a role in chromatin modification.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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