Thermo Fisher Scientific IL-4 Polyclonal Antibody
IL-4 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human과 Mouse 시료에 반응합니다. WB, IHC, Flow Cytometry 등 다양한 응용에 적합하며, 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (IHC) | - | View 10 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | View 1 publication |
| Flow Cytometry (Flow) | 1:10–1:50 | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 122–150 amino acids from the C-terminal region of human IL-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2542665 |
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and serves as a ligand for interleukin 4 receptor. IL-4 has a broad range of actions and shares overlapping functions with IL-13 due to receptor cross-binding. STAT6 plays a key role in mediating IL-4’s immune regulatory signal. The IL-4 gene, along with IL-3, IL-5, IL-13, and CSF2, forms a cytokine gene cluster on chromosome 5q. IL-4 is located near IL-13, and their expression is coordinated by long-range regulatory elements over a 120 kb region. IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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