
Thermo Fisher Scientific RND3 Polyclonal Antibody
RND3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며 Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human RND3, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras, Rho family members cycle between an inactive GDP-bound form and an active GTP-bound form.
Three major regulators of Rho activity have been identified:
- RhoGDIs: interact with GDP-bound Rho proteins to maintain them in a resting complex
- GEFs: promote GDP/GTP exchange leading to activation
- GAPs: stimulate GTP hydrolysis, returning Rho to its inactive form
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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