Thermo Fisher Scientific Cytokeratin 6 Polyclonal Antibody
Rabbit 유래의 Polyclonal 항체로 Human Cytokeratin 6B를 인식합니다. 케라틴 6 및 16 발현 연구에 적합하며, 피부 및 상피세포의 과증식 관련 연구에 활용됩니다. 액상 형태로 제공되며 4°C 보관, 장기 보관 시 -20°C 권장.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Cytokeratin 6B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640358 |
Product Specific Information
- Immunogen sequence: MASTSTTIRS HSSSRRGFSA NSARLPGVSR SGF
- Highest antigen sequence identity:
- Mouse: 61%
- Rat: 67%
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins).
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and in epidermis under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas, and its expression is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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