Thermo Fisher Scientific GORAB Polyclonal Antibody
Thermo Fisher Scientific의 GORAB Polyclonal Antibody는 인간 GORAB 단백질을 인식하는 토끼 IgG 기반 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 안정적인 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GORAB. Recombinant protein control fragment (Product #RP-94149) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642115 |
Product Specific Information
- Immunogen sequence:
MSWAAVLAVA AARFGHFWGC RWPGPMAQGW AGFSEEELRR LKQTKDPFEP QRRLPAKKSR QQLQREKALV EQSQKLGLQD GSTSLLPEQL LSAP - Highest antigen sequence identity to orthologs:
Mouse – 66%, Rat – 67%
Target Information
TCEB1, known as protein elongin C, is a subunit of the transcription factor B (SIII) complex composed of elongins A/A2, B, and C. This complex activates elongation by RNA polymerase II by suppressing transient pausing within transcription units.
Elongin A is the transcriptionally active component, while elongins B and C serve regulatory roles. Elongin A2 is testis-specific and forms stable complexes with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation.
Western blot analyses using two distinct antibodies against unique regions of this protein confirm consistent apparent molecular weight results.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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