Thermo Fisher Scientific Phospho-DAPK1 (Ser308) Polyclonal Antibody
DAPK1 단백질의 Ser308 인산화 형태를 특이적으로 검출하는 rabbit polyclonal antibody. Western blot에 최적화되어 있으며, 인간과 생쥐 시료에서 반응. 액상 형태로 제공되며, -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA564507
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DAPK1 (Phospho-Ser308) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2663874 |
Product Specific Information
Phospho-DAPK1 (Ser308) Polyclonal Antibody detects endogenous levels of DAPK1 only when phosphorylated at Ser308.
Target Information
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor.
It participates in multiple cellular signaling pathways that regulate cell survival, apoptosis, and autophagy.
DAPK1 controls both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell death signals.
It phosphorylates PIN1, inhibiting its catalytic activity and nuclear localization, and also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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