Thermo Fisher Scientific DUSP5 Monoclonal Antibody (OTI5H9), TrueMAB
DUSP5 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. Human과 Rat 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/BSA/glycerol 완충액에 보존되며 -20°C에서 안정적으로 보관 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 125–384 of human DUSP5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. Different members of this family show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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