Thermo Fisher Scientific CRISP2 Polyclonal Antibody
CRISP2 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체. Western blot 및 IHC(Paraffin) 실험에 최적화되어 있으며, 인간을 주요 반응종으로 함. 액상 형태, 0.5 mg/mL 농도, -20°C 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–1 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QHSDPEDRKTSTR) corresponding to internal amino acids of CRISP2 (aa 81–94) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10981011 |
Product Specific Information
- Predicted to react with canine, human, and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
The cysteine-rich secretory proteins (CRISP) family comprises four proteins strongly expressed in the male reproductive tract and implicated in male fertility.
CRISP2 (also known as TPX1) is involved in adhesion between spermatids and Sertoli cells and may play a role in sperm-egg fusion with CRISP1.
CRISP2 regulates Ca²⁺ influx through ryanodine receptors (RYR), potentially influencing acrosome reaction or sperm motility.
It also binds to MAP3K11 and localizes to the developing acrosome, suggesting a role in acrosome development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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