Thermo Fisher Scientific ZHX2 Polyclonal Antibody
Thermo Fisher Scientific의 ZHX2 Polyclonal Antibody는 Mouse ZHX2 단백질의 C-말단 영역을 타겟으로 하는 Rabbit IgG 폴리클로날 항체입니다. Western blot에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Thermo Fisher Scientific ZHX2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of mouse ZHX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691107 |
Product Specific Information
This target displays homology in the following species:
- Mouse: 100%
- Rat: 100%
Target Information
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers and heterodimers, although dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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